Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| BRCA | rs12386092 | chr18:44672058 | C/T | 6.71E-6 | 1026 | 21.73 | 21.58 | 18.13 | KM Plot |
| BRCA | rs12467000 | chr2:9520959 | C/T | 1.05E-7 | 1014 | 21.5 | 21.43 | 12.57 | KM Plot |
| BRCA | rs12480837 | chr20:30508331 | G/A | 5.55E-14 | 1018 | 21.28 | 23.8 | 8.5 | KM Plot |
| BRCA | rs12625069 | chr20:25114608 | G/A | 8.86E-8 | 1024 | 21.88 | 22.32 | 13.52 | KM Plot |
| BRCA | rs12667970 | chr7:130310844 | T/C | 3.01E-5 | 1024 | 22.4 | 19.8 | 17.93 | KM Plot |
| BRCA | rs12873937 | chr13:28194089 | T/A | 9.57E-8 | 1016 | 21.95 | 20.08 | 5.57 | KM Plot |
| BRCA | rs12963792 | chr18:1479688 | C/T | 1.34E-5 | 1028 | 21.17 | 26.13 | 19.67 | KM Plot |
| BRCA | rs13045280 | chr20:25104977 | A/T | 2.81E-5 | 1021 | 22.08 | 21.97 | 14.57 | KM Plot |
| BRCA | rs13065351 | chr3:46327512 | T/G | 3.08E-6 | 1027 | 22.03 | 18.43 | 20.4 | KM Plot |
| BRCA | rs13067058 | chr3:46273766 | C/T | 8.11E-6 | 1028 | 21.93 | 20.22 | 10.13 | KM Plot |
| BRCA | rs13068145 | chr3:46332276 | C/A | 3.07E-6 | 1027 | 22.08 | 18.4 | 20.4 | KM Plot |
| BRCA | rs13068271 | chr3:46332184 | G/A | 3.07E-6 | 1028 | 22.03 | 18.4 | 20.4 | KM Plot |
| BRCA | rs13068276 | chr3:46332190 | G/C | 3.07E-6 | 1028 | 22.03 | 18.4 | 20.4 | KM Plot |
| BRCA | rs13070099 | chr3:46253214 | T/C | 4.89E-7 | 1024 | 22.03 | 18.4 | 21.33 | KM Plot |
| BRCA | rs13071469 | chr3:46328627 | T/C | 3.08E-6 | 1027 | 22.03 | 18.43 | 20.4 | KM Plot |